Takeda S, Nanjo S, Nakamoto K, Imachi T, Yamamoto S
Department of Thoracic and Cardiovascular Surgery, Ehime National Hospital, Japan.
Respiration. 1994;61(2):113-6. doi: 10.1159/000196319.
We describe a case of carcinosarcoma of the lung in a 60-year-old female who was admitted with complaints of productive cough and an abnormal shadow in the chest X-ray. Sputum cytology showed both squamous cell carcinoma and adenocarcinoma cells. Malignant nonepithelial cells were identified in the needle biopsy specimen. Right middle and lower lobectomy was performed to reveal a carcinosarcoma by microscopic and immunohistochemical examination. This case was histologically unusual because it presented multiple carcinomatous elements (squamous cell carcinoma and adenocarcinoma). It was classified as peripheral type according to the clinical classification, showing an extremely poor prognosis. The histogenesis and clinical features of this rare tumor are discussed.
我们报告一例60岁女性肺肉瘤样癌病例，该患者因咳嗽咳痰及胸部X线检查发现异常阴影入院。痰细胞学检查显示既有鳞状细胞癌细胞又有腺癌细胞。针吸活检标本中发现了恶性非上皮细胞。行右肺中下叶切除术，经显微镜检查和免疫组化检查确诊为肉瘤样癌。该病例组织学表现不寻常，因为它呈现出多种癌性成分（鳞状细胞癌和腺癌）。根据临床分类，它被归类为周围型，预后极差。本文讨论了这种罕见肿瘤的组织发生及临床特征。
