Bergelin A, Subra J F, Carrere F, Chevailler A, Masson C, Szapiro N, Riberi P
Service de néphrologie, Centre hospitalier et universitaire, Angers.
Rev Med Interne. 1993;14(10):1024. doi: 10.1016/s0248-8663(05)80141-9.
We studied clinical and biological data of 18 patients presenting ANCA associated diseases for 16 months at least. Five relapses were preceded by ANCA elevation, 1 relapse was not. Four transient elevations were noted without any clinical event. We think ANCA level elevation by itself is not enough for deciding therapy intensification, clinical data are necessary for doing so.
我们研究了至少16个月来患有抗中性粒细胞胞浆抗体(ANCA)相关疾病的18例患者的临床和生物学数据。5次复发之前有ANCA升高,1次复发之前没有。记录到4次短暂升高但无任何临床事件。我们认为ANCA水平升高本身不足以决定强化治疗,为此需要临床数据。