[与胺碘酮相关的甲状腺功能障碍。对116例患者的前瞻性调查]
[Thyroid dysfunctions related to amiodarone. Prospective survey with 116 patients].
作者信息
Wemeau J L, Bauters C, Coviaux R, Anouilh A, Maillez T, D'herbomez M, Devemy F, Decoulx M
机构信息
Service de clinique médicale, USN A-CHRU, Lille.
出版信息
Rev Med Interne. 1993;14(10):955. doi: 10.1016/s0248-8663(05)80073-6.
PMID:8009051
Abstract
Thyroid hormones, TSH and antithyroid antibodies were prospectively controlled in 116 patients treated with amiodarone. Hypothyroidism occurred in 4 patients (3.7%) mainly early (average = 6 months). Hyperthyroidism was seen among 13 patients (11.9%) and its prevalence was proportional to therapy duration.
摘要
对116例接受胺碘酮治疗的患者前瞻性地监测了甲状腺激素、促甲状腺激素（TSH）和抗甲状腺抗体。4例患者（3.7%）发生了甲状腺功能减退，主要出现在早期（平均6个月）。13例患者（11.9%）出现了甲状腺功能亢进，其发生率与治疗持续时间成正比。
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