对西非马里耶利马内地区维生素A缺乏情况的评估。

Evaluation of vitamin A deficiency in the Yelimane Circle of Mali, west Africa.

作者信息

Perkins A L

机构信息

Projet Sante Oculaire, Mission Protestante, Yelimane, Mali, West Africa.

出版信息

Trop Doct. 1994 Apr;24(2):70-2. doi: 10.1177/004947559402400208.

DOI:10.1177/004947559402400208

PMID:8009618

Abstract

Of 207 children (aged 4-7 years) in western Mali examined clinically and by conjunctival impression cytology (CIC), 2% had night blindness, no child had Bitot spots and 78% were found to have abnormal CIC suggesting deficiency in vitamin A. In a cohort of 53 children examined by CIC pre- and post-harvest (June and December), abnormal CIC were seen in 77.4% and 54.7%, respectively (P = 0.04). Subclinical vitamin A deficiency is a problem in this area. A seasonal variation is demonstrated. CIC is a useful method for identifying communities with subclinical vitamin A deficiency. A variety of strategies for dealing with vitamin A deficiency are discussed.

摘要

在对马里西部207名4至7岁儿童进行临床检查和结膜印迹细胞学检查（CIC）后发现，2%的儿童有夜盲症，没有儿童有毕脱氏斑，78%的儿童CIC异常，提示维生素A缺乏。在一组53名儿童中，在收获前（6月）和收获后（12月）进行CIC检查，CIC异常的比例分别为77.4%和54.7%（P = 0.04）。亚临床维生素A缺乏在该地区是一个问题。研究显示存在季节性变化。CIC是识别亚临床维生素A缺乏社区的一种有用方法。文中还讨论了应对维生素A缺乏的各种策略。