Carmody R F, Mafee M F, Goodwin J A, Small K, Haery C
University of Arizona Medical Center, Tucson 85724.
AJNR Am J Neuroradiol. 1994 Apr;15(4):775-83.
To identify and characterize the MR findings of sarcoidosis when it involves the orbit and visual pathways.
The MR scans of 15 patients, 3 with presumed and 12 with proved orbital or optic pathway sarcoidosis were retrospectively reviewed.
Eight patients had MR evidence of optic nerve involvement by sarcoid granuloma. Perineural enhancement was seen in four cases, optic atrophy in one. Three who had had unenhanced scans showed optic nerve enlargement. Nine patients had optic chiasmal involvement. One patient had increased T2 signal in the optic radiations. Three patients had orbital masses that had MR signal characteristics similar to pseudotumor. Five patients had periventricular white matter abnormalities closely resembling multiple sclerosis.
Sarcoidosis should be considered in the differential diagnosis of optic nerve or nerve sheath enhancement on MR. Orbital sarcoidosis has MR characteristics very similar to pseudotumor.
识别并描述结节病累及眼眶及视觉通路时的磁共振成像（MR）表现。
回顾性分析15例患者的MR扫描结果，其中3例疑似眼眶或视神经通路结节病，12例确诊。
8例患者有MR证据显示结节病肉芽肿累及视神经。4例可见神经周围强化，1例有视神经萎缩。3例未增强扫描者显示视神经增粗。9例患者视交叉受累。1例患者视辐射T2信号增高。3例患者眼眶肿物的MR信号特征类似假瘤。5例患者脑室周围白质异常，酷似多发性硬化。
MR显示视神经或神经鞘强化时，鉴别诊断应考虑结节病。眼眶结节病的MR特征与假瘤非常相似。
