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芬兰双相情感障碍患者的自杀情况。

Suicide in bipolar disorder in Finland.

作者信息

Isometsä E T, Henriksson M M, Aro H M, Lönnqvist J K

机构信息

Department of Mental Health, National Public Health Institute, Helsinki, Finland.

出版信息

Am J Psychiatry. 1994 Jul;151(7):1020-4. doi: 10.1176/ajp.151.7.1020.

Abstract

OBJECTIVE

The authors examined suicides of persons with bipolar disorder in aspects relevant to suicide prevention, including clinical features, treatment contacts, adequacy of treatment received, communication of suicidal intent, and suicide methods.

METHODS

All suicide victims with DSM-III-R bipolar I disorder among all 1,397 suicides in Finland within a 12-month period were carefully studied using the psychological autopsy method and were compared to suicide victims with unipolar major depression.

RESULTS

Thirty-one bipolar I victims were identified. Most suicides of persons with bipolar disorder occurred during a major depressive episode (79%), but in some cases it occurred during a mixed state (11%) or even during or immediately after remission of psychotic mania (11%). Men had a higher rate of comorbid alcoholism, a lesser mean age, and shorter treatment histories than women. Although 74% of the victims were receiving psychiatric care at the time of suicide, and 39% had even explicitly communicated their intent to health care personnel during the last 3 months, only 11% of those who were depressed had received adequate doses of antidepressants and none had received ECT. Only 32% of the bipolar patients were prescribed lithium. In comparison to unipolar depressed suicide victims, the bipolar victims had more divorces, longer treatment histories, and more frequent hospitalizations.

CONCLUSIONS

Although late suicides were common among both male and female bipolar victims, suicide seemed to occur earlier among males. Most bipolar victims had had a recent psychiatric treatment contact, but few had received adequate treatment immediately before death. Suicide victims with unipolar and bipolar disorders differed in marital status and treatment history.

摘要

目的

作者从自杀预防的相关方面对双相情感障碍患者的自杀情况进行了研究,包括临床特征、治疗接触、所接受治疗的充分性、自杀意图的传达以及自杀方式。

方法

采用心理解剖法对芬兰12个月内1397例自杀案例中所有符合DSM - III - R双相I型障碍的自杀受害者进行了仔细研究,并与单相重度抑郁症自杀受害者进行了比较。

结果

共识别出31例双相I型障碍受害者。双相情感障碍患者的自杀大多发生在重度抑郁发作期间(79%),但在某些情况下发生在混合状态期间(11%),甚至在精神病性躁狂缓解期或缓解后不久(11%)。男性共病酒精中毒的发生率更高,平均年龄更小,治疗史比女性更短。虽然74%的受害者在自杀时正在接受精神科护理,39%的人甚至在过去3个月内向医护人员明确表达了自杀意图,但抑郁患者中只有11%接受了足够剂量的抗抑郁药,且无人接受过电休克治疗。只有32%的双相情感障碍患者被开了锂盐。与单相抑郁自杀受害者相比,双相情感障碍受害者离婚更多,治疗史更长,住院更频繁。

结论

虽然晚期自杀在双相情感障碍男性和女性受害者中都很常见,但男性自杀似乎发生得更早。大多数双相情感障碍受害者近期有过精神科治疗接触,但很少有人在死前接受过充分治疗。单相和双相情感障碍自杀受害者在婚姻状况和治疗史方面存在差异。

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