Isometsä E T, Henriksson M M, Aro H M, Heikkinen M E, Kuoppasalmi K I, Lönnqvist J K
National Public Health Institute, Department of Mental Health, Helsinki, Finland.
Am J Psychiatry. 1994 Apr;151(4):530-6. doi: 10.1176/ajp.151.4.530.
The purpose of this study was to examine a sample representing all suicide victims with current DSM-III-R major depression in Finland within 1 year in aspects relevant to suicide prevention, including comorbidity, clinical history, current treatment, suicide methods, and communication of suicide intent.
Using the psychological autopsy method, the authors examined all 71 suicide victims with current unipolar DSM-III-R major depression, taken from a random sample of 229 subjects representing 16.4% of all suicide victims in Finland in 1 year.
The majority (85%) were complicated cases with comorbid diagnoses, and comorbidity varied according to the subjects' sex and age. Three-quarters had a history of psychiatric treatment, but only 45% were receiving psychiatric treatment at the time of death. Most suicide victims had received no treatment for depression. Only 3% had received antidepressants in adequate doses, 7% weekly psychotherapy, and 3% ECT. None of the 24 psychotic subjects had received adequate psychopharmacological treatment. Few (8%) had used an antidepressant overdose as a suicide method. Men had received less treatment for depression and had more commonly used violent suicide methods.
Although about half of the suicide victims with major depression were receiving psychiatric care at the time of death, few were receiving adequate treatment for depression. There were significant sex differences in current and previous treatment and suicide methods. For suicide prevention in major depression, it would seem crucial to improve treatment and follow-up, for males with major depression, in particular.
本研究旨在对芬兰一年内所有符合《精神疾病诊断与统计手册》第三版修订版(DSM-III-R)中重度抑郁症的自杀受害者样本进行检查,涉及自杀预防的相关方面,包括共病情况、临床病史、当前治疗、自杀方式以及自杀意图的传达。
作者采用心理解剖法,对所有71名符合DSM-III-R中单相重度抑郁症的自杀受害者进行了检查,这些受害者取自229名受试者的随机样本,该样本占芬兰一年内所有自杀受害者的16.4%。
大多数(85%)为伴有共病诊断的复杂病例,共病情况因受试者的性别和年龄而异。四分之三的人有精神科治疗史,但死亡时只有45%的人正在接受精神科治疗。大多数自杀受害者未接受过抑郁症治疗。只有3%的人接受了足够剂量的抗抑郁药治疗,7%的人接受了每周一次的心理治疗,3%的人接受了电休克治疗。24名精神病患者中无人接受过足够的精神药物治疗。很少有人(8%)将过量服用抗抑郁药作为自杀方式。男性接受的抑郁症治疗较少,更常采用暴力自杀方式。
虽然约一半患有重度抑郁症的自杀受害者在死亡时正在接受精神科护理,但很少有人接受了足够的抑郁症治疗。在当前和既往治疗以及自杀方式方面存在显著的性别差异。对于重度抑郁症的自杀预防而言,改善治疗和随访似乎至关重要,尤其是对于患有重度抑郁症的男性。