Moore J A, Faith R E
Environ Health Perspect. 1976 Dec;18:125-31. doi: 10.1289/ehp.7618125.
The potential harmful effects of toxic compounds on the developing immune system are discussed. This discussion is illustrated by results of studies of the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the developing immune system of Fischer rats. While this compound and several others have been shown to have immunosuppressive effects, the available data do not support routine evaluation of the consequence of chemical exposure to the developing immune system.
本文讨论了有毒化合物对发育中免疫系统的潜在有害影响。以2,3,7,8-四氯二苯并对二恶英对Fischer大鼠发育中免疫系统影响的研究结果为例进行了阐述。虽然已证明该化合物及其他几种化合物具有免疫抑制作用,但现有数据并不支持对化学物质暴露于发育中免疫系统的后果进行常规评估。