1992年2月在中非共和国分离出的A群脑膜炎奈瑟菌菌株的特征
Characteristics of serogroup A Neisseria meningitidis strains isolated in the Central African Republic in February 1992.
作者信息
Guibourdenche M, Caugant D A, Hervé V, Debonne J M, Lanckriet C, Merlin M, Mathiot C, Roungou J B, Martet G, Riou J Y
机构信息
Unité des Neisseria, Institut Pasteur, Paris, France.
出版信息
Eur J Clin Microbiol Infect Dis. 1994 Feb;13(2):174-7. doi: 10.1007/BF01982194.
A severe epidemic of serogroup A meningococcus meningitis occurred in the northwest Central African Republic from January to March 1992. Strains from 24 patients were characterized using serotyping, testing of susceptibility to antibiotics, and multilocus enzyme electrophoresis. In 23 of the 24 patients the causal strain was found to be 4:P1.9/clone III-1. These results indicate that such strains continue to spread in Africa and have taken hold in areas outside the "meningitis belt." This may be a consequence of changing climatic conditions.
1992年1月至3月，中非共和国西北部发生了A群脑膜炎球菌性脑膜炎的严重疫情。对24名患者的菌株进行了血清分型、抗生素敏感性测试和多位点酶电泳分析。在24名患者中的23名中，发现致病菌株为4:P1.9/克隆III-1。这些结果表明，此类菌株在非洲持续传播，并在“脑膜炎带”以外的地区扎根。这可能是气候条件变化的结果。
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