Shibata A, Mack T M, Paganini-Hill A, Ross R K, Henderson B E
Department of Preventive Medicine, University of Southern California School of Medicine, Los Angeles.
Int J Cancer. 1994 Jul 1;58(1):46-9. doi: 10.1002/ijc.2910580109.
Risk factors for pancreatic cancer were examined in a cohort study of 13,979 residents of a retirement community. After 9 years of follow-up, 65 incident cases of pancreatic cancer were identified. An increased risk of pancreatic cancer was associated with a history of diabetes and cholecystectomy. Higher intake of vegetables, fruits, dietary beta-carotene, and vitamin C were each associated with a reduced risk of pancreatic cancer, although none of these associations was statistically significant. Risk of pancreatic cancer decreased with increasing tea consumption but was unrelated to coffee consumption. No strong or consistent association was seen between either smoking or alcohol consumption and risk of pancreatic cancer, but a consistent and significant increase in risk followed cholecystectomy.
在一项针对某退休社区13979名居民的队列研究中，对胰腺癌的风险因素进行了调查。经过9年的随访，共确诊65例胰腺癌新发病例。胰腺癌风险增加与糖尿病史和胆囊切除术有关。蔬菜、水果、膳食β-胡萝卜素和维生素C的摄入量较高均与胰腺癌风险降低有关，尽管这些关联均无统计学意义。胰腺癌风险随茶消费量的增加而降低，但与咖啡消费量无关。吸烟或饮酒与胰腺癌风险之间均未发现强烈或一致的关联，但胆囊切除术后风险持续且显著增加。
