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一只雪貂中由鸟分枝杆菌引起的肉芽肿性肠炎。

Granulomatous enteritis caused by Mycobacterium avium in a ferret.

作者信息

Schultheiss P C, Dolginow S Z

机构信息

Department of Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523.

出版信息

J Am Vet Med Assoc. 1994 Apr 15;204(8):1217-8.

PMID:8014091
Abstract

Granulomatous enteritis caused by Mycobacterium avium was diagnosed in a pet ferret evaluated for anorexia, vomiting, and diarrhea. Delayed gastric emptying was identified during barium sulfate contrast radiography. A constriction in the duodenum, which was an area of granulomatous inflammation on histologic examination, was surgically removed. After removal of this lesion, the ferret did well for 8 months, but clinical signs returned. At a second surgery, a nodule was removed from the pylorus. The ferret died 2 weeks later. At necropsy, granulomatous inflammation, with acid-fast organisms, was found in the pylorus, small intestine, mesenteric lymph nodes, liver, and spleen. Mycobacterium avium was isolated from specimens of liver and spleen. Ferrets can develop clinical disease caused by M avium, and infected ferrets may pose public health threats.

摘要

一只因厌食、呕吐和腹泻接受评估的宠物雪貂被诊断出患有由鸟分枝杆菌引起的肉芽肿性肠炎。在硫酸钡造影检查中发现胃排空延迟。十二指肠出现狭窄,组织学检查显示该区域为肉芽肿性炎症,遂通过手术将其切除。切除该病变后,雪貂状况良好地存活了8个月,但临床症状再次出现。在第二次手术中,从幽门处切除了一个结节。两周后这只雪貂死亡。尸检时,在幽门、小肠、肠系膜淋巴结、肝脏和脾脏中发现了伴有抗酸菌的肉芽肿性炎症。从肝脏和脾脏标本中分离出了鸟分枝杆菌。雪貂可发生由鸟分枝杆菌引起的临床疾病,受感染的雪貂可能对公共卫生构成威胁。

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