Miller J E
Office of Population Research, Princeton University.
J Biosoc Sci. 1994 Apr;26(2):243-59. doi: 10.1017/s0021932000021271.
This study examines the effects of birth order and interpregnancy interval on birthweight, gestational age, weight-for-gestational age, infant length, and weight-for-length in a sample of 2063 births from a longitudinal study in the Philippines. First births are the most disadvantaged of any birth order/spacing group. The risks associated with short intervals (< 6 months) and high birth order (fifth or higher) are confined to infants who have both attributes; there is no excess risk associated with short previous intervals among lower-order infants, nor for high birth order infants conceived after longer intervals. This pattern is observed for all five birth outcomes and neonatal mortality, and persists in models that control for mother's age, education, smoking, family health history and nutritional status. Since fewer than 2% of births are both short interval and high birth order, the potential reduction in the incidence of low birthweight or neonatal mortality from avoiding this category of high-risk births is quite small (1-2%).
本研究在菲律宾一项纵向研究的2063例出生样本中,考察了出生顺序和妊娠间隔对出生体重、孕周、出生体重与孕周比、婴儿身长以及身长体重比的影响。头胎出生的婴儿在任何出生顺序/间隔分组中都是最弱势的。与短间隔(<6个月)和高出生顺序(第五胎及以上)相关的风险仅限于同时具备这两个特征的婴儿;低出生顺序婴儿中,前次妊娠间隔短并无额外风险,间隔较长后生育的高出生顺序婴儿也没有额外风险。在所有五项出生结局和新生儿死亡率方面均观察到这种模式,并且在控制了母亲年龄、教育程度、吸烟情况、家族健康史和营养状况的模型中依然存在。由于间隔短且出生顺序高的出生情况不到2%,通过避免这类高危出生情况来降低低出生体重或新生儿死亡率的潜在幅度相当小(1%-2%)。