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正常衰老和不同病因痴呆症中记忆缺陷的差异模式。

The differential pattern of memory deficit in normal aging and dementias of different etiology.

作者信息

Mitrushina M, Satz P, Drebing C, Van Gorp W, Mathews A, Harker J, Chervinsky A

机构信息

UCLA School of Medicine, California State University, Northridge Olive View/UCLA Medical Center.

出版信息

J Clin Psychol. 1994 Mar;50(2):246-52. doi: 10.1002/1097-4679(199403)50:2<246::aid-jclp2270500216>3.0.co;2-l.

Abstract

The study explored encoding, storage, and retrieval components of memory functioning in four groups of subjects: (1) normal elderly; (2) elderly subjects in the early prestages of DAT; (3) elderly subjects with a more advanced DAT; (4) younger subjects in the early prestages of AIDS dementia. Each group consisted of 26 subjects, who were administered the Rey Auditory-Verbal Learning Test. The results suggest impaired encoding and retrieval in the DAT groups. The AIDS group demonstrated deficient storage and retrieval. Their pattern of memory deficits was similar to that seen in normal aging. The results speak in favor of the hypothesis of subcortical nature of neurological changes in normal aging.

摘要

该研究探讨了四组受试者记忆功能的编码、存储和检索成分:(1) 正常老年人;(2) 处于 DAT 早期前期阶段的老年受试者;(3) 患有更晚期 DAT 的老年受试者;(4) 处于艾滋病痴呆早期前期阶段的年轻受试者。每组由 26 名受试者组成,他们接受了雷伊听觉语言学习测试。结果表明 DAT 组存在编码和检索受损。艾滋病组表现出存储和检索不足。他们的记忆缺陷模式与正常衰老中所见的相似。结果支持了正常衰老中神经变化具有皮质下性质的假说。

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