Arimura A
Nihon Naibunpi Gakkai Zasshi. 1976 Nov 20;52(11):1159-83. doi: 10.1507/endocrine1927.52.11_1159.
Recent experimental and clinical studies LH-RH and somatostatin were presented. Immunological approaches, such as determination of these hypothalamic hormones in the tissue and blood by RIA, immunohistochemical studies, and active or passive immunization of animals with LH-RH or somatostatin, provided much useful information on the physiological roles of these hormones. LH-RH has been found to be useful not only for diagnosis of various diseases but also for treatment of some type of hypogonadisms. Experimental data on somatostatin suggest a considerable potential for practical application of somatostatin in the clinical field. However, the possible suppressive effect of somatostatin on platelet aggregation should be seriously considered when it is used for clinical purposes.
介绍了近期有关促黄体生成素释放激素（LH - RH）和生长抑素的实验及临床研究。免疫方法，如通过放射免疫分析（RIA）测定组织和血液中的这些下丘脑激素、免疫组织化学研究以及用LH - RH或生长抑素对动物进行主动或被动免疫，为这些激素的生理作用提供了许多有用信息。已发现LH - RH不仅对各种疾病的诊断有用，而且对某些类型的性腺功能减退症的治疗也有用。关于生长抑素的实验数据表明其在临床领域有相当大的实际应用潜力。然而，当生长抑素用于临床时，应认真考虑其对血小板聚集可能的抑制作用。
