Tajiri A, Taki K, Chou W P, Chung I S, Terasaki H, Morioka T
Department of Anesthesiology, Kumamoto, University School of Medicine.
Masui. 1994 May;43(5):740-5.
We studied the effects on hemolysis of our manually operated, portable cardiopulmonary bypass system with two self-inflatable reservoir-pumps in parallel by using bovine blood. The blood shed from both the jugular vein and the carotid artery, immediately after slaughter, was divided into three plastic containers, one for the control, one for manual circulation, and the other for conventional circulation with a roller-pump. Small bore catheters were intentionally placed into the inflow and outflow routes of both circulation systems to simulate clinical situations. Free hemoglobin and potassium in plasma were measured every 30 min during the experimental circulation for 120 min. The free hemoglobin in plasma increased gradually under manual circulation, but this increase was statistically insignificant when compared with the variances of those in the conventional circulation and the control blood groups. The values of the potassium in the plasma showed no differences among the three blood groups. Our manually operated, portable cardiopulmonary bypass system will be a valuable adjunct for emergency medicine.
我们使用牛血研究了我们的手动便携式体外循环系统（带有两个并联的自动充气储血泵）对溶血的影响。宰杀后立即从颈静脉和颈动脉采集的血液被分成三个塑料容器，一个用于对照，一个用于手动循环，另一个用于使用滚压泵的传统循环。故意在两个循环系统的流入和流出路径中放置小孔径导管以模拟临床情况。在120分钟的实验循环期间，每30分钟测量一次血浆中的游离血红蛋白和钾。在手动循环下，血浆中的游离血红蛋白逐渐增加，但与传统循环和对照血组中的游离血红蛋白变化相比，这种增加在统计学上无显著意义。三个血组的血浆钾值没有差异。我们的手动便携式体外循环系统将成为急诊医学的一种有价值的辅助设备。
