Gubernatorov E E, Gerasimov G A, Bershinskiĭ V P, Pivovarov S A, Orlov K V
Probl Endokrinol (Mosk). 1993 Mar-Apr;39(2):22-4.
Age-specific time course of prolactin secretion and features of dopaminergic regulation of this hormone secretion were studied in boys aged 3 to 15 and in adult men aged 20 to 25. Blood plasma prolactin concentration was found reduced in boys, and this hormone level, characteristic for adults, sets up at the age of 9-11. Dopaminergic regulation of prolactin secretion undergoes three stages in boys: Stage 1--hyperreaction to introduction of a receptor antagonist at the age of 3 to 8, Stage 2--at the age of 9 to 11--reduced reaction to D2 receptor blocking, though this reaction being much higher than in adults, and Stage 3 (at the age of 12-15)--development of a normal reaction characteristic of adults.
研究了3至15岁男孩以及20至25岁成年男性催乳素分泌的年龄特异性时间进程及其多巴胺能调节特征。发现男孩血浆催乳素浓度降低，而成人特有的这种激素水平在9至11岁时确立。男孩催乳素分泌的多巴胺能调节经历三个阶段：第一阶段（3至8岁）——对引入受体拮抗剂反应过度；第二阶段（9至11岁）——对D2受体阻断反应降低，尽管该反应仍远高于成年人；第三阶段（12至15岁）——出现成年人特有的正常反应。
