Lai M H, Bard M, Kirsch D R
American Cyanamid, Agricultural Reseach Division, Princeton, NJ 08543-0400.
Yeast. 1994 Mar;10(3):399-402. doi: 10.1002/yea.320100313.
A Saccharomyces cerevisiae sequence cloned by serendipity was found to encode a protein that is a new member of the Ypt/Rab monomeric G-protein family. This sequence shows high homology to the yeast genes SEC4 and YPT1 and, like SEC4 and YPT1, is essential for viability. The sequence was localized to chromosome V based upon hybridization to pulse-field gel-separated yeast chromosomes. The sequence has been deposited in the GenBank data library under Accession Number L17070.
偶然克隆出的一个酿酒酵母序列被发现编码一种蛋白质，该蛋白质是Ypt/Rab单体G蛋白家族的新成员。此序列与酵母基因SEC4和YPT1具有高度同源性，并且与SEC4和YPT1一样，对细胞活力至关重要。基于与脉冲场凝胶分离的酵母染色体杂交，该序列被定位到第五条染色体上。该序列已以登录号L17070存入GenBank数据库。
