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来自酿酒酵母的一个基因,该基因编码一种与细菌3-磷酸丝氨酸转氨酶具有显著同源性的蛋白质。

A gene from Saccharomyces cerevisiae which codes for a protein with significant homology to the bacterial 3-phosphoserine aminotransferase.

作者信息

Belhumeur P, Fortin N, Clark M W

机构信息

Department of Microbiology and Immunology, University of Montreal, Quebec, Canada.

出版信息

Yeast. 1994 Mar;10(3):385-9. doi: 10.1002/yea.320100311.

DOI:10.1002/yea.320100311
PMID:8017107
Abstract

During the sequencing of the gene GSP2 from Saccharomyces cerevisiae, we have encountered an adjacent open reading frame having strong homology to the 3-phosphoserine aminotransferase (E.C.2.6.1.52) from other organisms. In this report, we present the sequence for this yeast SERC, and evidence that its deletion from the yeast genome leads to serine dependency. The sequence has been deposited in the GenBank data library under Accession Number L20917.

摘要

在对酿酒酵母的GSP2基因进行测序过程中,我们遇到了一个与其他生物的3-磷酸丝氨酸转氨酶(E.C.2.6.1.52)具有高度同源性的相邻开放阅读框。在本报告中,我们展示了该酵母SERC的序列,以及从酵母基因组中缺失该序列会导致丝氨酸依赖性的证据。该序列已存入GenBank数据库,登录号为L20917。

相似文献

1
A gene from Saccharomyces cerevisiae which codes for a protein with significant homology to the bacterial 3-phosphoserine aminotransferase.来自酿酒酵母的一个基因,该基因编码一种与细菌3-磷酸丝氨酸转氨酶具有显著同源性的蛋白质。
Yeast. 1994 Mar;10(3):385-9. doi: 10.1002/yea.320100311.
2
Cloning and sequencing of the NES24 gene of Saccharomyces cerevisiae.酿酒酵母NES24基因的克隆与测序
Yeast. 1994 Mar;10(3):371-6. doi: 10.1002/yea.320100309.
3
CLG1, a new cyclin-like gene of Saccharomyces cerevisiae.CLG1,酿酒酵母的一个新的类细胞周期蛋白基因。
Yeast. 1993 Aug;9(8):929-31. doi: 10.1002/yea.320090813.
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A Saccharomyces servazzii clone homologous to Saccharomyces cerevisiae chromosome III spanning KAR4, ARS 304 and SPB1 lacks the recombination enhancer but contains an unknown ORF.一个与酿酒酵母第三条染色体同源、跨越KAR4、ARS 304和SPB1的塞尔瓦齐酵母克隆缺乏重组增强子,但含有一个未知的开放阅读框。
Yeast. 2001 Jun 30;18(9):789-95. doi: 10.1002/yea.724.
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Sequence of the open reading frame of the FLO1 gene from Saccharomyces cerevisiae.来自酿酒酵母的FLO1基因开放阅读框的序列。
Yeast. 1993 Apr;9(4):423-7. doi: 10.1002/yea.320090413.
6
LTE1 of Saccharomyces cerevisiae is a 1435 codon open reading frame that has sequence similarities to guanine nucleotide releasing factors.酿酒酵母的LTE1是一个由1435个密码子组成的开放阅读框,与鸟嘌呤核苷酸释放因子具有序列相似性。
Yeast. 1994 Jul;10(7):953-8. doi: 10.1002/yea.320100710.
7
Sequence analysis of a 9873 bp fragment of the left arm of yeast chromosome XV that contains the ARG8 and CDC33 genes, a putative riboflavin synthase beta chain gene, and four new open reading frames.对酵母第十五号染色体左臂上一段9873 bp的片段进行序列分析,该片段包含ARG8和CDC33基因、一个假定的核黄素合酶β链基因以及四个新的开放阅读框。
Yeast. 1995 Sep 15;11(11):1061-7. doi: 10.1002/yea.320111107.
8
Cloning, sequencing and disruption of the ARG8 gene encoding acetylornithine aminotransferase in the petite-negative yeast Kluyveromyces lactis.在小菌落阴性乳酸克鲁维酵母中编码乙酰鸟氨酸转氨酶的ARG8基因的克隆、测序及破坏。
Yeast. 1998 Feb;14(3):281-5. doi: 10.1002/(SICI)1097-0061(199802)14:3<281::AID-YEA212>3.0.CO;2-E.
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Identification of gene encoding a putative RNA-helicase, homologous to SKI2, in chromosome VII of Saccharomyces cerevisiae.在酿酒酵母七号染色体中鉴定出一个与SKI2同源的假定RNA解旋酶编码基因。
Yeast. 1997 Mar 30;13(4):391-7. doi: 10.1002/(SICI)1097-0061(19970330)13:4<391::AID-YEA92>3.0.CO;2-Q.
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Cloning and sequence of REV7, a gene whose function is required for DNA damage-induced mutagenesis in Saccharomyces cerevisiae.酿酒酵母中DNA损伤诱导诱变所需功能基因REV7的克隆与序列分析
Yeast. 1994 Nov;10(11):1503-9. doi: 10.1002/yea.320101115.

引用本文的文献

1
Characterization of human phosphoserine aminotransferase involved in the phosphorylated pathway of L-serine biosynthesis.参与L-丝氨酸生物合成磷酸化途径的人磷酸丝氨酸转氨酶的特性分析。
Biochem J. 2003 Jul 1;373(Pt 1):191-200. doi: 10.1042/BJ20030144.
2
Molecular cloning, characterization and expression of cDNA encoding phosphoserine aminotransferase involved in phosphorylated pathway of serine biosynthesis from spinach.菠菜中参与丝氨酸生物合成磷酸化途径的磷酸丝氨酸转氨酶编码cDNA的分子克隆、特性分析及表达
Plant Mol Biol. 1997 Jan;33(2):359-66. doi: 10.1023/a:1005730725764.
3
A multipurpose transposon system for analyzing protein production, localization, and function in Saccharomyces cerevisiae.
一种用于分析酿酒酵母中蛋白质产生、定位和功能的多功能转座子系统。
Proc Natl Acad Sci U S A. 1997 Jan 7;94(1):190-5. doi: 10.1073/pnas.94.1.190.