在接受长期抗胆碱酯酶治疗的重症肌无力患者中，于丙泊酚 - 芬太尼 - 氧化亚氮/氧气麻醉期间对琥珀胆碱的反应。
Response to suxamethonium during propofol-fentanyl-N2O/O2 anaesthesia in a patient with active myasthenia gravis receiving long-term anticholinesterase therapy.
作者信息
Vanlinthout L E, Robertson E N, Booij L H
机构信息
Institute for Anaesthesiology, University Hospital of Nijmegen, The Netherlands.
出版信息
Anaesthesia. 1994 Jun;49(6):509-11. doi: 10.1111/j.1365-2044.1994.tb03523.x.
Abstract
We describe the effect of repeated suxamethonium doses during propofol-fentanyl-N2O/O2 anaesthesia in a 29-year-old woman with active myasthenia gravis receiving chronic pyridostigmine therapy. Despite adequate pre-operative pseudocholinesterase activity, suxamethonium resistance occurred. Neither bradycardia nor residual neuromuscular block were seen after repeated doses of suxamethonium.
摘要
我们描述了在丙泊酚-芬太尼-氧化亚氮/氧气麻醉期间，对一名接受慢性吡啶斯的明治疗的29岁重症肌无力活动期女性重复给予琥珀胆碱的效果。尽管术前假性胆碱酯酶活性充足，但仍出现了琥珀胆碱耐药。重复给予琥珀胆碱后，既未出现心动过缓，也未观察到残余神经肌肉阻滞。
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