Günther T, Vormann J, Konstanczak P, Schäfer A
Institut für Molekularbiologie und Biochemie, Freie Universität Berlin, Germany.
Biochim Biophys Acta. 1994 Jun 22;1192(2):281-5. doi: 10.1016/0005-2736(94)90129-5.
Polyamines, particularly spermine, in physiological concentrations interact with mag-fura-2 and the mag-fura-2/Mg2+ complex, resulting in reduced values of free Mg2+ concentration. Similarly, polyamines interact with ATP and MgATP. Thus, free Mg2+ concentration, as measured by 31P-NMR or mag-fura-2, is underestimated in the presence of polyamines, particularly of spermine.
