Díaz-Plasencia J, Vilela Desposorio C, Rebaza-Iparraguirre H, Villacorta Acosta R, Calipuy Abanto W
Servicio de Cirugía Oncológica, Hospital de Belén, Trujillo, Perú.
Rev Gastroenterol Peru. 1994 Jan-Apr;14(1):22-6.
This retrospective analysis evaluated 25 patients with benign polypoid lesions and 2 cases with malignant polyps of the gallbladder who had undergone cholecystectomy at Belén Hospital, Trujillo, Perú, from January, 1966 through December, 1993 in a attempt to elucidate the clinicopathological aspects of these patients. Cholelithiasis and cholesterolosis were present as associated findings in about 68% and 12% of patients respectively. The median age was of 48.8 +/- 15 years, the male:female ratio was 1:4, a right upper quadrant pain was the most common symptom (100%) and nonvisualization of a diseased gallbladder was seen in about 44% of cholecystograms. Microscopically, the lesions were classified as follow: Hyperplasias (n = 11), adenomas (n = 10), cholesterol polyps (n = 2), inflammatory polyps (n = 2) and malignant polyps (n = 2). Seventy six percent of benign lesions measured less than 0.5 cm and 12% were multiple lesions. The average diameter of malignant polyps was larger than 3 cm. We concluded that the benign epithelial tumors of the gallbladder are extremely rare cases and the treatment of choice for adenomatous polyps should be surgical for the possibility of developing malignant transformation.
这项回顾性分析评估了1966年1月至1993年12月期间在秘鲁特鲁希略的贝伦医院接受胆囊切除术的25例胆囊良性息肉样病变患者和2例胆囊恶性息肉患者,旨在阐明这些患者的临床病理特征。胆石症和胆固醇沉着症分别在约68%和12%的患者中作为相关发现存在。中位年龄为48.8±15岁,男女比例为1:4,右上腹疼痛是最常见症状(100%),约44%的胆囊造影显示病变胆囊不显影。显微镜下,病变分类如下:增生(n = 11)、腺瘤(n = 10)、胆固醇息肉(n = 2)、炎性息肉(n = 2)和恶性息肉(n = 2)。76%的良性病变直径小于0.5 cm,12%为多发病变。恶性息肉的平均直径大于3 cm。我们得出结论,胆囊良性上皮性肿瘤极为罕见,腺瘤性息肉的首选治疗方法应为手术,因为其有发生恶变的可能。