Ino T, Okamoto M, Tsuzuki M, Kamino I, Hirano M
Department of Medicine, Fujita Health University School of Medicine, Aichi, Japan.
Int J Hematol. 1994 Feb;59(2):131-5.
A 43-year-old male developed acute myelogenous leukemia (AML, M5b) with an acquired Robertsonian 13;15 translocation. He did not achieve complete remission after sequential intensive induction chemotherapy and he died 13 months later. We reviewed 7 patients with this translocation reported in the literature. Acquired Robertsonian translocations are rare, but could represent an important event in the tumorigenesis of hematologic malignancies.
一名43岁男性患急性髓系白血病(AML,M5b型),伴有后天性罗伯逊易位13;15。在序贯强化诱导化疗后未达到完全缓解,13个月后死亡。我们回顾了文献中报道的7例有这种易位的患者。后天性罗伯逊易位很少见,但可能是血液系统恶性肿瘤发生过程中的一个重要事件。