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急性髓系白血病(M5b)中一种获得性13;15罗伯逊易位。

An acquired Robertsonian 13;15 translocation in acute myelogenous leukemia (M5b).

作者信息

Ino T, Okamoto M, Tsuzuki M, Kamino I, Hirano M

机构信息

Department of Medicine, Fujita Health University School of Medicine, Aichi, Japan.

出版信息

Int J Hematol. 1994 Feb;59(2):131-5.

PMID:8018906
Abstract

A 43-year-old male developed acute myelogenous leukemia (AML, M5b) with an acquired Robertsonian 13;15 translocation. He did not achieve complete remission after sequential intensive induction chemotherapy and he died 13 months later. We reviewed 7 patients with this translocation reported in the literature. Acquired Robertsonian translocations are rare, but could represent an important event in the tumorigenesis of hematologic malignancies.

摘要

一名43岁男性患急性髓系白血病(AML,M5b型),伴有后天性罗伯逊易位13;15。在序贯强化诱导化疗后未达到完全缓解,13个月后死亡。我们回顾了文献中报道的7例有这种易位的患者。后天性罗伯逊易位很少见,但可能是血液系统恶性肿瘤发生过程中的一个重要事件。

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引用本文的文献

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[Acute promyelocytic leukaemia with translocations of t(15;17)(q22;q21) and rob(13;21): a case report and literatures review].[伴t(15;17)(q22;q21)易位及rob(13;21)的急性早幼粒细胞白血病:1例报告并文献复习]
Zhonghua Xue Ye Xue Za Zhi. 2015 Jan;36(1):16-9. doi: 10.3760/cma.j.issn.0253-2727.2015.01.004.