Mallik A K, Ferrell W R, McDonald A G, Sturrock R D
Institute of Physiology, University of Glasgow.
Br J Rheumatol. 1994 Jul;33(7):631-7. doi: 10.1093/rheumatology/33.7.631.
Twelve patients with the hypermobility syndrome (> or = 4 on the Beighton score) were examined to establish whether they showed any impairment of proprioception. A position matching paradigm was used which required subjects to align a finger silhouette with the kinaesthetically perceived position of their hidden index finger. Position sense at the PIP joint was found to be significantly (P < 0.0001) impaired in hypermobile patients who made larger matching errors at all angles compared to age- and sex-matched controls. The patients also demonstrated biasing in the direction of errors made when the PIP joint was positioned +/- 20 degrees away from the mid-position. These patients perceived the PIP joint to be less displaced towards the extremes of the range of movement than it really was. The mechanism underlying this impairment of proprioception remains speculative and it is not clear whether this disturbance is a cause or an effect of the hypermobility syndrome.
对12名患有活动过度综合征（Beighton评分≥4分）的患者进行了检查，以确定他们是否存在本体感觉障碍。采用了一种位置匹配范式，要求受试者将手指轮廓与他们隐藏的食指的动觉感知位置对齐。结果发现，与年龄和性别匹配的对照组相比，活动过度的患者在所有角度的匹配误差都更大，其近端指间关节（PIP）的位置觉明显受损（P<0.0001）。当PIP关节偏离中间位置±20度时，患者在误差方向上也表现出偏差。这些患者感觉到PIP关节向运动范围极限的位移比实际情况要小。本体感觉受损的潜在机制仍具有推测性，目前尚不清楚这种紊乱是活动过度综合征的原因还是结果。
