Wexler L H, Helman L J
Solid Tumor Section, National Cancer Institute, Bethesda, Maryland.
CA Cancer J Clin. 1994 Jul-Aug;44(4):211-47. doi: 10.3322/canjclin.44.4.211.
Soft tissue sarcomas are the sixth most common cancer in children and collectively account for about seven percent of all pediatric cancers. The development of increasingly intensive, multimodality treatment protocols for these tumors has led to a steady increase in cure rates for these neoplasms, especially for rhabdomyosarcoma, the most common pediatric soft tissue sarcoma. This article provides an overview of the basic biology, clinical management, and clinical research for pediatric soft tissue sarcomas.
软组织肉瘤是儿童中第六大常见癌症，约占所有儿科癌症的7%。针对这些肿瘤的强化多模式治疗方案不断发展，使得这些肿瘤的治愈率稳步提高，尤其是横纹肌肉瘤，这是最常见的儿科软组织肉瘤。本文概述了儿科软组织肉瘤的基础生物学、临床管理和临床研究。
