Andreyev H J, Owen R A, Thompson I, Forbes A
St Mark's Hospital, London.
Gut. 1994 Jun;35(6):788-90. doi: 10.1136/gut.35.6.788.
The operation notes and pathology records of 294 consecutive patients who had right hemicolectomy for Crohn's disease were reviewed. A Meckel's diverticulum was found in 17 (5.8%) of these patients, 2-3 times the expected rate in the general population. At least 50% of diverticula in the normal population contain heterotopic mucosa, but none was found in those diverticula that were examined from this group. The increased prevalence of Meckel's diverticulum in patients with Crohn's disease confirms previous anecdotal reports, but the cause for the increased frequency remains unexplained. The significance of this finding is discussed.
回顾了294例因克罗恩病接受右半结肠切除术的连续患者的手术记录和病理记录。在这些患者中,有17例(5.8%)发现了梅克尔憩室,这是普通人群预期发生率的2至3倍。正常人群中至少50%的憩室含有异位黏膜,但在该组接受检查的憩室中未发现一例。克罗恩病患者中梅克尔憩室患病率的增加证实了之前的传闻报道,但频率增加的原因仍无法解释。本文讨论了这一发现的意义。