Soltero M J, Bill A H
Am J Surg. 1976 Aug;132(2):168-73. doi: 10.1016/0002-9610(76)90043-x.
To determine the natural history of Meckel's diverticulum, 202 case records of proved disease of Meckel's diverticulum were retrieved, covering a fifteen year period, from all the hospitals of King County, Washington (population, 1,143,800). Using the figure of 2 per cent incidence of Meckel's diverticulum, we calculated that a Meckel's diverticulum has a 4.2 per cent likelihood of causing disease during a lifetime, decreasing to zero with old age. Using previously published mortality and morbidity figures, we calculated that to save one patient's life from the complications of Meckel's diverticulum, it would be necessary to remove approximately 800 asymptomatic Meckel's diverticula. This would be likely to incur a significant amount of postoperative morbidity from postoperative intestinal obstruction and infection. We suggest that the prophylactic removal of Meckel's diverticulum is rarely, if ever, justified.
为了确定梅克尔憩室的自然病史,我们从华盛顿州金县所有医院(人口1,143,800)中检索了202例经证实的梅克尔憩室疾病病例记录,时间跨度为15年。根据梅克尔憩室2%的发病率,我们计算出梅克尔憩室在一生中引发疾病的可能性为4.2%,随着年龄增长降至零。利用先前公布的死亡率和发病率数据,我们计算出要从梅克尔憩室并发症中挽救一名患者的生命,大约需要切除800个无症状的梅克尔憩室。这很可能会因术后肠梗阻和感染而导致大量术后发病。我们认为,预防性切除梅克尔憩室几乎没有(如果有的话)正当理由。