Jehn U
Medizinische Klinik, Klinikum Grosshadern der Universität München.
Fortschr Med. 1994 May 10;112(13):180-4.
The myelodysplastic syndrome (MDS) and myeloproliferative syndrome (MPS), together with chronic lymphatic leukemia (CLL) are, for the most part, seen in the elderly. Chronic myeloid leukemia (CML), however, is not common in this age group. New treatment for the myelodysplastic syndrome is the use of cytokines, for CLL fludarabine, and 2-chloro-2-deoxy-adenosine (2-CDA). The standard form of treatment for CML and other myeloproliferative syndromes is interferon alpha or hydroxyurea, or a combination of the two.
骨髓增生异常综合征(MDS)、骨髓增殖性综合征(MPS)以及慢性淋巴细胞白血病(CLL)大多见于老年人。然而,慢性髓性白血病(CML)在这个年龄组并不常见。治疗骨髓增生异常综合征的新方法是使用细胞因子,治疗CLL则使用氟达拉滨和2-氯-2-脱氧腺苷(2-CDA)。治疗CML和其他骨髓增殖性综合征的标准方法是使用α干扰素或羟基脲,或两者联合使用。