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迪本多夫研究:一项基于人群的血压自测正常值调查。

The Dübendorf Study: a population-based investigation on normal values of blood pressure self-measurement.

作者信息

Weisser B, Grüne S, Burger R, Blickenstorfer H, Iseli J, Michelsen S H, Opravil R, Rageth S, Sturzenegger E R, Walker P

机构信息

Department of Internal Medicine, University Hospital, Zürich, Switzerland.

出版信息

J Hum Hypertens. 1994 Apr;8(4):227-31.

PMID:8021901
Abstract

There is evidence that self-measurement of BP increases precision, reproducibility and prognostic value of BP measurement. However, generally accepted normal values for BP values obtained by self-measurement are still missing. The present study was undertaken to investigate differences between office and self-measured blood pressure; 503 randomly selected inhabitants (265 men and 238 women, age 20-90 years, mean age 46.5 +/- 12.9 years) of the small town of Dübendorf in Switzerland were studied. The subjects were not preselected according their BP levels, only patients taking antihypertensive drugs were excluded. Self-measurement was performed at home by the subjects during 14 days in the morning between 6 and 8 am and in the evening between 6 and 8 pm (mean of 26.7 measurements). Office BP was taken before and after the two week period. Mean office BP (130.0 +/- 16.5/82.1 +/- 11.1 mmHg) was significantly (P < 0.01) higher than mean self-measured BP (123.1 +/- 14.6/77.6 +/- 10.7 mmHg). There was no significant difference between first and second office BP measurement. Morning self-measured BP was lower than evening pressure (delta 4.0/1.4 mmHg, both P < 0.01) and the mean was taken for comparison with office BP.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

有证据表明,血压的自我测量可提高血压测量的精确度、可重复性及预后价值。然而,通过自我测量获得的血压值的普遍公认正常范围仍未确定。本研究旨在调查诊室血压与自我测量血压之间的差异;对瑞士迪本多夫小镇随机选取的503名居民(265名男性和238名女性,年龄20 - 90岁,平均年龄46.5±12.9岁)进行了研究。受试者未根据其血压水平预先挑选,仅排除正在服用抗高血压药物的患者。受试者在家中于早上6点至8点和晚上6点至8点之间的14天内进行自我测量(平均测量26.7次)。在两周时间段前后测量诊室血压。诊室平均血压(130.0±16.5/82.1±11.1 mmHg)显著高于自我测量平均血压(123.1±14.6/77.6±10.7 mmHg)(P<0.01)。第一次和第二次诊室血压测量之间无显著差异。早晨自我测量血压低于晚上血压(差值4.0/1.4 mmHg,均P<0.01),并取平均值用于与诊室血压作比较。(摘要截短于250字)

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