Chinushi M, Aizawa Y, Kusano Y, Washizuka T, Miyajima T, Naitho N, Takahashi K, Shibata A
First Department of Internal Medicine, Niigata University School of Medicine, Japan.
Jpn Circ J. 1994 May;58(5):315-25. doi: 10.1253/jcj.58.315.
Radiofrequency current catheter ablation was attempted for 17 morphologies of ventricular tachycardia (VT) in 14 patients. Five patients had underlying heart disease. The site of VT origin was determined as the earliest site of ventricular activation, or by pacing within the area of slow conduction. In 15 VTs, ablation was performed during VT, and 12 VTs (80%) were terminated within an average of 5.4 +/- 4.2 seconds. After ablation, 14 VTs (14/17 = 82%) of 11 patients (11/14 = 79%) could not be induced by electrical stimulation. Radiofrequency ablation appeared to be more effective in VTs without underlying heart disease (91%), and in VTs originating from the right ventricle (100%). Successful ablation sites usually showed a normal local electrograms during VT. Ablation in the slow conduction area was attempted in 3 VTs, and 2 VTs became noninducible. The mean number of applications of radiofrequency current for each VT origin was 7.7 +/- 6.4 at 20-50 Watts. In 4 patients, application of radiofrequency current was required 10 or more times because of a possible large arrhythmogenic area, or because of reinduction of VT, even though VT was terminated by radiofrequency current. No major complication was observed except for complete right bundle branch block in 1 patient.
(1) Radiofrequency catheter ablation was considered to be effective and safe, especially for VT without underlying heart disease or VT originating from the right ventricle. (2) Ablation during VT was considered to be useful for identifying the proper ablation site and to avoid creating an unnecessary lesion.
对14例患者的17种室性心动过速(VT)形态尝试进行射频电流导管消融。5例患者有基础心脏病。VT起源部位确定为心室激动最早部位,或通过在缓慢传导区域内起搏来确定。在15例VT中,在VT发作时进行消融,12例VT(80%)平均在5.4±4.2秒内终止。消融后,11例患者(11/14 = 79%)中的14例VT(14/17 = 82%)不能被电刺激诱发。射频消融在无基础心脏病的VT(91%)以及起源于右心室的VT(100%)中似乎更有效。成功的消融部位在VT发作时通常显示局部电图正常。对3例VT尝试在缓慢传导区域进行消融,2例VT变为不能被诱发。每个VT起源部位的射频电流平均应用次数为7.7±6.4次,功率为20 - 50瓦。在4例患者中,由于可能存在较大的致心律失常区域,或由于VT再次诱发,尽管VT被射频电流终止,但仍需要10次或更多次应用射频电流。除1例患者出现完全性右束支传导阻滞外,未观察到严重并发症。
(1)射频导管消融被认为是有效且安全的,尤其对于无基础心脏病的VT或起源于右心室的VT。(2)在VT发作时进行消融被认为有助于确定合适的消融部位并避免造成不必要的损伤。