King B M, Sam H, Arceneaux E R, Kass J M
Department of Psychology, University of New Orleans, LA 70148.
Physiol Behav. 1994 May;55(5):963-6. doi: 10.1016/0031-9384(94)90087-6.
Bilateral lesions centered in the posterodorsal amygdala of female rats resulted in hyperphagia and excessive weight gain. The brain damage extended posteriorly through the amygdalohippocampal area and into the ventral hippocampus and subiculum. Lesions centered in the ventral hippocampal formation had a less pronounced, although still significant, effect on body weight. Damage to large areas of the amygdala, including the anterior, basolateral, and corticomedial groups of nuclei, was without effect. A serial reconstruction of overlapping areas of destruction for both effective and ineffective lesions is presented.
以雌性大鼠杏仁核后背部为中心的双侧损伤导致食欲亢进和体重过度增加。脑损伤向后延伸穿过杏仁核海马区，进入腹侧海马和海马下脚。以腹侧海马结构为中心的损伤对体重的影响虽不那么明显，但仍很显著。包括杏仁核前核、基底外侧核和皮质内侧核群在内的大面积杏仁核损伤则没有影响。本文展示了有效和无效损伤重叠破坏区域的系列重建图。
