Zhavoronkova L A, Kholodova N B, Zubovskiĭ G A, Smirnov Iu N, Koptelov Iu M, Ryzhov N I
Zh Vyssh Nerv Deiat Im I P Pavlova. 1994 Mar-Apr;44(2):229-38.
EEG mapping and three-dimensional localization of epileptic activity sources together with a neurological analysis were carried out in subjects having taken part in 1986-1987 in the liquidation of consequences of the Chernobyl accident. Experimental group included 40 right-handed 25-45 years-old men having received a radiation dose of 15-51 Ber stated officially. Control group consisted of 20 healthy men. Neurological examination of the patients revealed vegetative-vascular and endocrine dysfunctions as well as diffuse neurological symptoms. EEG of one group of patients (25 persons) was characterized by slow alpha- and theta-band foci and epileptic waves in the central-frontal regions; epileptic sources were localized at the diencephalic level mainly in the midline being shifted to the right hemisphere. In the EEG of another group (15 persons) delta-waves were recorded in the frontal regions at the background of diffuse beta-activity. The sources of epileptic activity of a diffuse character were localized at the basal level of the brain and in the cortex (predominantly) in the left hemisphere. The results obtained together with SPECT mapping and CT data permit to suppose the organic damage of different brain structures (at the cortical and the midline levels) in the patients, with participation of diencephalic structures in the pathological process hypothalamic-hypophysial system being probably connected with adaptive processes in the CNS.
对1986 - 1987年参与切尔诺贝利事故后果清理工作的受试者进行了脑电图映射和癫痫活动源的三维定位,并结合神经学分析。实验组包括40名右利手、25至45岁的男性,官方称他们接受的辐射剂量为15至51贝可。对照组由20名健康男性组成。对患者的神经学检查发现了植物神经血管和内分泌功能障碍以及弥漫性神经症状。一组患者(25人)的脑电图特征为中央 - 额叶区域出现慢α和θ波段病灶以及癫痫波;癫痫源主要定位于间脑水平,中线部位为主,向右半球偏移。另一组(15人)的脑电图在弥漫性β活动背景下,额叶区域记录到δ波。弥漫性癫痫活动源定位于脑底部以及大脑皮层(主要在左半球)。所获得的结果连同单光子发射计算机断层扫描(SPECT)映射和计算机断层扫描(CT)数据表明,患者不同脑结构(皮层和中线水平)存在器质性损伤,间脑结构参与了病理过程,下丘脑 - 垂体系统可能与中枢神经系统的适应性过程有关。