Kutner N G, Lin L S, Fielding B, Brogan D, Hall W D
Department of Rehabilitation Medicine, School of Medicine, Emory University, Atlanta, GA 30322.
Am J Kidney Dis. 1994 Jul;24(1):42-9. doi: 10.1016/s0272-6386(12)80158-2.
This study investigated whether social and/or psychologic factors help to predict older dialysis patients' continued survival. A stratified (by race and sex) random sample of patients aged 60+ years was selected from the ESRD Network census of all patients in that age category residing in a single southeastern state (Georgia) and receiving chronic dialysis as of November 1987; personal interviews with patients were completed in 1988. This analysis includes 287 patients (mean age, 69 years) receiving outpatient hemodialysis for whom primary cause of renal failure and functional status data were complete. Patient tracking and vital statistics data determined that 49% of the sample survived as of October 31, 1990. Study variables included demographic, dialysis, health status, social situation, and psychologic outlook variables reported at the patients' 1988 interviews. Log rank tests showed univariate associations between patients' continued survival and race/gender, recovery time following dialysis treatments, cardiovascular co-morbidity, exercise activity score, freedom from health limitation of daily activity, functional status, leisure activity score, self-rated health status, overall life satisfaction, depression, and public religiosity. The Cox proportional hazards model was fit to the data, with continued survival from the time of the 1988 interview as the dependent variable. There was a significantly increased mortality risk for white men relative to the other race/gender groups and for patients reporting severely impaired functional status at the 1988 interview. With functional status in the model, no other social or psychologic variables were significant predictors of mortality.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究调查了社会和/或心理因素是否有助于预测老年透析患者的持续生存情况。从居住在东南部一个州(佐治亚州)且截至1987年11月接受慢性透析的60岁及以上患者的终末期肾病网络普查中,选取了一个按种族和性别分层的随机样本;1988年完成了对患者的个人访谈。该分析纳入了287例接受门诊血液透析的患者(平均年龄69岁),这些患者肾衰竭的主要病因和功能状态数据完整。患者追踪和生命统计数据显示,截至1990年10月31日,49%的样本存活。研究变量包括在1988年患者访谈中报告的人口统计学、透析、健康状况、社会状况和心理状况变量。对数秩检验显示,患者的持续生存与种族/性别、透析治疗后的恢复时间、心血管合并症、运动活动评分、日常活动无健康限制、功能状态、休闲活动评分、自评健康状况、总体生活满意度、抑郁和公众宗教信仰之间存在单变量关联。将Cox比例风险模型应用于这些数据,以1988年访谈时间起的持续生存作为因变量。相对于其他种族/性别组,白人男性以及在1988年访谈中报告功能状态严重受损的患者,其死亡风险显著增加。在模型中纳入功能状态后,没有其他社会或心理变量是死亡的显著预测因素。(摘要截短至250字)