Bauduceau B, Reboul P, Le Guyadec T, Legrelle M, Mayaudon H, Gautier D
Service d'Endocrinologie, HIA Bégin, Saint-Mandé.
Ann Endocrinol (Paris). 1993;54(3):163-7.
Gynecomastia, a very frequent disorder, is present in almost 40% of young men. In this population the investigations often fail to find any aetiology, therefore defining idiopathic gynecomastia. The aim of this work is to compare clinical and hormonal characteristics of 488 subjects with gynecomastia to 41 healthy controls. Their are many explanations for the occurrence of idiopathic gynecomastia, including modification of hormonal balance, change of aromatase activity, or a receptor anomaly. Our works demonstrate a significant decrease in mean testosteronemia, linked to a high prevalence of incipient hypogonadism in the studied population, especially in patients with an history of testicular disease.
男性乳房肥大是一种非常常见的病症，几乎40%的年轻男性都有此症状。在这一群体中，调查往往找不到任何病因，因此定义为特发性男性乳房肥大。这项研究的目的是比较488名男性乳房肥大患者与41名健康对照者的临床和激素特征。对于特发性男性乳房肥大的发生有许多解释，包括激素平衡的改变、芳香化酶活性的变化或受体异常。我们的研究表明，平均睾酮血症显著降低，这与研究人群中初期性腺功能减退的高患病率有关，尤其是有睾丸疾病史的患者。
