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[喀麦隆农村地区加碘盐对学龄儿童地方性甲状腺肿的治疗效果]

[Effects of iodized salt in the treatment of endemic goiter in school children in a rural environment in Cameroon].

作者信息

Ngogang J, Meli J, Carteret P

机构信息

Département des Sciences Physiologiques, Yaoundé 1, Cameroun.

出版信息

Ann Endocrinol (Paris). 1993;54(3):191-6.

PMID:8024245
Abstract

The efficiency of iodized salt in Cameroon has been tested during 7 months in school children living in an endemic goitrous area. The salt contained 150 mg of iodine per kilogramme of salt when it left the production site. The regression rate of goiter was 84.0% and was not different from that obtained with a single oral administration of 240 mg of iodized oil to an age and sex matched population. Excretion of iodine in urine increased significantly (P < 0.05). Eight biochemical cases of thyroid dysfunction (7 cases of hypothyroidism and 1 case of hyperthyroidism) were observed. However these observations do not preclude the use of iodized salt in the prevention and the treatment of goiter in endemic areas.

摘要

在喀麦隆,对生活在地方性甲状腺肿流行地区的学童进行了为期7个月的碘盐效果测试。盐离开生产地时,每千克盐含150毫克碘。甲状腺肿的消退率为84.0%,与对年龄和性别匹配人群单次口服240毫克碘油所获得的消退率没有差异。尿碘排泄显著增加(P<0.05)。观察到8例甲状腺功能障碍的生化病例(7例甲状腺功能减退和1例甲状腺功能亢进)。然而,这些观察结果并不妨碍在地方性甲状腺肿流行地区使用碘盐来预防和治疗甲状腺肿。

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