A yeast artificial chromosome contig on mouse chromosome 11 encompassing the nu locus.
作者信息
Nehls M, Lüno K, Schorpp M, Krause S, Matysiak-Scholze U, Prokop C M, Hedrich H J, Boehm T
机构信息
Department of Medicine I, University of Freiburg, Germany.
出版信息
Eur J Immunol. 1994 Jul;24(7):1721-3. doi: 10.1002/eji.1830240742.
PMID:8026534
Abstract
Mutations at the nude locus disrupt the homing process of T cell progenitor cells to the thymic rudiment, a key aspect of T cell differentiation. Here, we map the nude locus to a set of overlapping yeast artificial chromosomes (YAC) clones covering a genetic interval of about 0.5 centi Morgan on mouse chromosome 11. These results provide a suitable starting point to molecularly clone the nude gene.
摘要
Zotero 插件