用流产布鲁氏菌19或RB51疫苗接种的牛布鲁氏菌病诊断试验中的血清学反应。
Serologic responses in diagnostic tests for brucellosis in cattle vaccinated with Brucella abortus 19 or RB51.
作者信息
Stevens M G, Hennager S G, Olsen S C, Cheville N F
机构信息
Brucellosis Research Unit, U.S. Department of Agriculture, Ames, Iowa 50010.
出版信息
J Clin Microbiol. 1994 Apr;32(4):1065-6. doi: 10.1128/jcm.32.4.1065-1066.1994.
Abstract
Serologic responses in the particle concentration fluorescence immunoassay and the card, complement fixation, and tube agglutination tests were measured for 10 weeks after vaccination of cattle with either Brucella abortus 19 or the lipopolysaccharide O-antigen-deficient mutant, strain RB51. The responses of strain 19-vaccinated cattle were positive, whereas those of strain RB51-vaccinated cattle were negative, in all of the tests. These results indicate that cattle vaccinated with strain RB51 fail to produce antibodies that can be detected by conventional serologic tests that are used to diagnose bovine brucellosis.
摘要
在用布鲁氏菌19株或脂多糖O抗原缺陷型突变株RB51对牛进行疫苗接种后的10周内，检测了颗粒浓度荧光免疫测定法以及卡片法、补体结合试验和试管凝集试验中的血清学反应。在所有试验中，接种19株疫苗的牛的反应呈阳性，而接种RB51株疫苗的牛的反应呈阴性。这些结果表明，用RB51株疫苗接种的牛不能产生可通过用于诊断牛布鲁氏菌病的传统血清学试验检测到的抗体。
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