Lauer K, Munshi C, Larson S
Department of Anesthesiology, Medical College of Wisconsin, Milwaukee 53226.
J Clin Monit. 1994 May;10(3):181-4. doi: 10.1007/BF02908858.
To quantify the effect of an induction dose of midazolam on median nerve somatosensory evoked potentials.
We studied 10 patients undergoing lumbar spine surgery. After an induction dose of intravenous midazolam was given, MNEPs were collected for ten minutes. After ten minutes the patients were intubated and their anesthetic was supplemented with 0.5% isoflurane, narcotic, and N2O.
We found a clinically significant decrease in amplitude and an insignificant delay in latency.
When midazolam is used as an anesthetic induction agent, a decrease in amplitude can be expected.
量化诱导剂量的咪达唑仑对正中神经体感诱发电位的影响。
我们研究了10例接受腰椎手术的患者。静脉给予诱导剂量的咪达唑仑后，采集正中神经体感诱发电位10分钟。10分钟后，患者进行气管插管，并补充0.5%异氟醚、麻醉剂和氧化亚氮。
我们发现波幅出现了具有临床意义的下降，潜伏期延迟不显著。
当咪达唑仑用作麻醉诱导剂时，可预期波幅会降低。
