Smith T G, Desser S S, Hong H
Department of Zoology, University of Toronto, Ontario, Canada.
J Wildl Dis. 1994 Apr;30(2):169-75. doi: 10.7589/0090-3558-30.2.169.
Inclusions characteristic of an infection caused by Toddia sp. were found in the erythrocytes and erythroblasts of 15 of 26 northern water snakes (Nerodia sipedon sipedon) collected near Kingston, Ontario, Canada. Erythrocytes contained translucent inclusions, small acidophilic bodies, and square-shaped crystalloid structures. Erythrocytes infected with Toddia sp. were more rounded than uninfected erythrocytes and had pycnotic nuclei. We observed icosahedral virus particles measuring 195 to 210 nm formed from a membrane-bounded viral assembly site in the cytoplasm of the host erythrocyte. As a result of the viral identity of this parasite, we recommend that the etiologic agent of Toddia sp. infections from this and other species of North American snakes be renamed Snake Erythrocytic Virus.
在加拿大安大略省金斯顿附近采集的26条北水蛇（Nerodia sipedon sipedon）中，有15条的红细胞和成红细胞中发现了托迪亚属（Toddia sp.）感染特有的包涵体。红细胞含有半透明包涵体、小嗜酸性体和方形晶体结构。感染托迪亚属的红细胞比未感染的红细胞更圆，且细胞核固缩。我们观察到在宿主红细胞细胞质中由膜结合病毒装配位点形成的二十面体病毒颗粒，大小为195至210纳米。鉴于这种寄生虫的病毒特性，我们建议将来自北美这种蛇及其他蛇类的托迪亚属感染的病原体重新命名为蛇红细胞病毒。
