Telford S R, Jacobson E R
Florida Museum of Natural History, University of Florida, Gainesville 32611.
J Wildl Dis. 1993 Jan;29(1):57-63. doi: 10.7589/0090-3558-29.1.57.
Giemsa-stained peripheral blood films from 9 of 50 flap-necked chameleons, Chamaeleo dilepis, and 1 of 18 Fischer's chameleons, Bradypodion fischeri, collected in Tanzania had intraerythrocytic inclusions. In C. dilepis, acidophilic inclusions were associated with the albuminoid vacuoles reported in typical pirhemocytonosis of saurians. Under transmission electron microscopy, the acidophilic inclusions were aggregations of partially or completely formed viral particles consistent with those of the family Iridoviridae. Enveloped viral particles were 140 to 180 nm in diameter, with a mean of 159 nm (SD, 12). Albuminoid vacuoles were not seen in the B. fischeri infection, in which erythrocytes contained multiple acidophilic inclusions of variable shape. Viral particles in B. fischeri were 156.3 to 200.0 nm in diameter; the mean was 180 nm (SD, 18). This represents the first confirmation of the viral identity of pirhemocyton in a lizard. We recommend that the epithet pirhemocyton no longer be used as a generic name under the International Code of Zoological Nomenclature, and that future reports of the etiologic agent refer to it as Lizard Erythrocytic Virus.
在坦桑尼亚采集的50只三角变色龙（Chamaeleo dilepis）中的9只以及18只费氏变色龙（Bradypodion fischeri）中的1只的吉姆萨染色外周血涂片中有红细胞内包涵体。在三角变色龙中，嗜酸性包涵体与蜥蜴典型梨形血细胞增多症中报道的类蛋白液泡有关。在透射电子显微镜下，嗜酸性包涵体是部分或完全形成的病毒颗粒的聚集物，与虹彩病毒科的病毒颗粒一致。有包膜的病毒颗粒直径为140至180纳米，平均为159纳米（标准差为12）。在费氏变色龙感染中未见到类蛋白液泡，其红细胞含有多个形状各异的嗜酸性包涵体。费氏变色龙中的病毒颗粒直径为156.3至200.0纳米；平均为180纳米（标准差为18）。这是首次在蜥蜴中确认梨形血细胞的病毒身份。我们建议，根据《国际动物命名法规》，“梨形血细胞”这一名称不再用作通用名称，且未来关于病原体的报告应将其称为蜥蜴红细胞病毒。
