Wong R W, Rappaport W D, Witzke D B, Putnam C W, Hunter G C
Department of Surgery, VA Medical Center, Tucson, Arizona 85723.
J Surg Res. 1994 Aug;57(2):289-92. doi: 10.1006/jsre.1994.1147.
Although colostomy closure is a commonly performed surgical procedure, there remains concern that the attendant risks may be misjudged, especially in the elderly. The purpose of this study was to evaluate the safety of performing colostomy closure and to define the factors that may influence morbidity and mortality in patients over the age of 70. Three hundred seven patients (178 males, 129 females) underwent colostomy closure over a 5-year period. The mean age was 52 years and 84 (27%) of the patients were 70 years or older. The indications for colostomy included diverticulitis, 115 (38%); malignancy, 47 (15%); perforation 35 (11%); trauma, 34 (11%); congenital anomalies, 26 (8%); obstruction, 13 (4%); bleeding, 6 (2%); colovesical fistulae, 6 (2%); polyps, 2 (0.7%); and miscellaneous, 23 (8%). An end colostomy was performed in 193 (63%) patients and a transverse loop colostomy in the remaining 114 (37%). There were no deaths. Complications occurred in 27 (9%) patients: 17 were directly related to colostomy closure (8 wound infections, 3 intraabdominal abscesses, 3 small bowel obstructions, 2 anastomotic strictures, and 1 anastomotic leak) while 10 were nonsurgical. Risk factors statistically associated with increased morbidity included age > 70 years (13% versus 5%), end versus loop colostomy (10% versus 2%), an operative time > 2 hr, and estimated blood loss > or = 500 ml (P < 0.05). ASA classification was only predicative of postoperative complications in patients over 70 years of age. We conclude that although colostomy closure can be performed without mortality, the increased morbidity associated with this procedure in patients 70 years or older necessitates careful preoperative assessment.
尽管结肠造口关闭术是一种常见的外科手术,但人们仍然担心其伴随的风险可能被误判,尤其是在老年人中。本研究的目的是评估进行结肠造口关闭术的安全性,并确定可能影响70岁以上患者发病率和死亡率的因素。在5年期间,307例患者(178例男性,129例女性)接受了结肠造口关闭术。平均年龄为52岁,其中84例(27%)患者年龄在70岁及以上。结肠造口的适应证包括憩室炎115例(38%);恶性肿瘤47例(15%);穿孔35例(11%);创伤34例(11%);先天性畸形26例(8%);梗阻13例(4%);出血6例(2%);结肠膀胱瘘6例(2%);息肉2例(0.7%);其他23例(8%)。193例(63%)患者行端式结肠造口术,其余114例(37%)行横袢式结肠造口术。无死亡病例。27例(9%)患者发生并发症:17例与结肠造口关闭直接相关(8例伤口感染、3例腹腔内脓肿、3例小肠梗阻、2例吻合口狭窄和1例吻合口漏),10例为非手术并发症。与发病率增加有统计学关联的危险因素包括年龄>70岁(13%对5%)、端式与袢式结肠造口术(10%对2%)、手术时间>2小时以及估计失血量>或=500 ml(P<0.05)。美国麻醉医师协会(ASA)分级仅对70岁以上患者的术后并发症有预测作用。我们得出结论,尽管结肠造口关闭术可无死亡发生,但70岁及以上患者该手术相关发病率增加,因此术前需要仔细评估。