Matthew I R, Browne R M, Frame J W, Millar B G
University of Birmingham, School of Dentistry.
Oral Surg Oral Med Oral Pathol. 1994 May;77(5):456-60. doi: 10.1016/0030-4220(94)90223-2.
The aim of this study was to evaluate the effect on hemostasis and wound healing of a proprietary alginate fiber dressing when applied to a wound of the buccal mucosa of approximately 2 mm depth. The study showed a significant reduction in the number of residual bleeding points in shallow wounds when the alginate fiber dressing was applied for 5 minutes as compared with the use of non-alginate-impregnated surgical gauze. There was no significant difference in the rate of epithelial repair of the test and control sites nor in the area of the resulting mucosal scar. In addition, there was no significant difference in the numbers of tissue components in the submucosa. It is concluded that the alginate fiber dressing material evaluated in this study may be effective as a hemostatic mucosal dressing in shallow wounds, but it does not accelerate mucosal wound healing.
本研究的目的是评估一种专利藻酸盐纤维敷料应用于深度约为2毫米的颊粘膜伤口时对止血和伤口愈合的影响。研究表明，与使用未浸渍藻酸盐的手术纱布相比，藻酸盐纤维敷料应用5分钟时，浅伤口的残留出血点数量显著减少。试验组和对照组部位的上皮修复率以及所形成的粘膜瘢痕面积均无显著差异。此外，粘膜下层的组织成分数量也无显著差异。得出的结论是，本研究中评估的藻酸盐纤维敷料材料可能作为浅伤口的止血粘膜敷料有效，但它不会加速粘膜伤口愈合。
