Matthew I R, Browne R M, Frame J W, Millar B G
University of Birmingham, School of Dentistry, St Chad's Queensway.
Br J Oral Maxillofac Surg. 1993 Jun;31(3):165-9. doi: 10.1016/0266-4356(93)90117-f.
Kaltostat is a new haemostatic wound dressing composed of non-woven sodium calcium alginate fibres, and was originally developed to cover exposed wounds of the skin. A histopathological study was undertaken to determine the tissue response to Kaltostat in healing tooth sockets, to obtain a comparison with oxidised regenerated cellulose (Surgicel). Tooth sockets filled with blood clot acted as controls. The results showed that both biomaterials delayed wound healing in the early phase (1-4 weeks), giving rise to foreign body reactions. At 12 weeks there was little difference between the control sockets and the sockets containing the test materials, although remnants of retained dressing materials were identified. Healing of the tooth sockets was complete at 24 weeks.
卡尔托斯塔（Kaltostat）是一种新型止血伤口敷料，由非织造的海藻酸钠钙纤维组成，最初是为覆盖皮肤暴露伤口而研发的。进行了一项组织病理学研究，以确定卡尔托斯塔在愈合牙槽窝时的组织反应，并与氧化再生纤维素（ Surgicel）进行比较。充满血凝块的牙槽窝作为对照。结果表明，两种生物材料在早期阶段（1 - 4周）均延迟伤口愈合，引发异物反应。在12周时，对照牙槽窝与含有测试材料的牙槽窝之间差异不大，尽管发现了残留的敷料材料。牙槽窝在24周时完全愈合。
