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[健康受试者服用去甘草酸甘草甜素和生胃酮后胃泌素、肾素、醛固酮及电解质的变化]

[Behavior of gastrin, renin, aldosterone and electrolytes after administration of deglycyrrhizinized liquorice and carbenoxolone in healthy subjects].

作者信息

Baas E U, Holtermüller K H, Sinterhauf K, Walter U

机构信息

I. Med. Klinik und Poliklinik, Johannes-Gutenberg-Universität, Mainz.

出版信息

Z Gastroenterol. 1976 Apr;14(2):273-6.

PMID:802922
Abstract

We found that renin and aldosterone values do not drop except when administering Carbenoxolone. The significant rise of sodium (11) in the serum and the drop of the serum-potassium values are probably responsible for the undesirable Carbenoxolone side effects; they occur following the administration of deglycyrrhizinized succus. The rise of post-prandial gastrin in the serum of the above as compared to the values obtained from untreated controls is common to both.

摘要

我们发现,除了给予甘草次酸外,肾素和醛固酮值不会下降。血清中钠(11)的显著升高和血清钾值的下降可能是甘草次酸不良副作用的原因;它们在给予去甘草酸的甘草汁后出现。与未治疗的对照组相比,上述人群血清中餐后胃泌素的升高在两者中都很常见。

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