Cannon D S, Leeka J K, Block A K
Psychology Service (116B), Department of Veterans Affairs Medical Center, Dallas, TX 75216.
Pharmacol Biochem Behav. 1994 Apr;47(4):795-802. doi: 10.1016/0091-3057(94)90279-8.
Initial self-administration of high doses of EtOH is shown to be associated in some inbred rat strains with the eventual development of a low preference for EtOH, presumably as a consequence of taste aversion learning occurring during initial intake. Only modest support was obtained for the hypothesis that strain differences in the aversiveness of EtOH affects taste aversion learning. The instrinsic palatability of EtOH and the salience of EtOH as a conditioned stimulus may also affect EtOH preference, but there do not appear to be differences among strains in their general ability to form taste-toxicosis associations.
高剂量乙醇的初始自我给药在一些近交系大鼠中显示与最终对乙醇的低偏好发展有关，这可能是由于初始摄入期间发生的味觉厌恶学习。关于乙醇厌恶程度的品系差异影响味觉厌恶学习这一假设，仅获得了适度的支持。乙醇的内在适口性以及乙醇作为条件刺激的显著性也可能影响乙醇偏好，但在形成味觉 - 中毒关联的一般能力方面，品系之间似乎没有差异。
