大鼠部分肝切除术后氨基酸对白蛋白合成的刺激作用。

Stimulation of albumin synthesis by amino acids following partial hepatectomy in the rat.

作者信息

Kirsch R E, Lloyd E A, Frith L O, Gordon B, Saunders S J

机构信息

University of Cape Town, Department of Medicine, Observatory, Cape, South Africa.

出版信息

Am J Clin Nutr. 1975 Dec;28(12):1412-5. doi: 10.1093/ajcn/28.12.1412.

DOI:10.1093/ajcn/28.12.1412

PMID:803003

Abstract

Albumin synthesis was measured, in vivo, in rats 16 hours after partial hepatectomy or after sham operation. When albumin synthesis was expressed in terms of whole body weight, partially hepatectomized rats synthesized significantly less than sham-operated rats. However, when albumin synthesis was expressed as a function of dry liver weight, the two groups synthesized similar amounts. Intragastric hyperalimentation with amino acids significantly increased albumin synthesis in partially hepatectomized rats.

摘要

在大鼠部分肝切除术后或假手术后16小时，对其体内白蛋白合成进行了测定。当以全身体重表示白蛋白合成时，部分肝切除的大鼠合成量明显低于假手术大鼠。然而，当以肝干重为函数表示白蛋白合成时，两组合成量相似。对部分肝切除的大鼠进行氨基酸胃内高营养显著增加了白蛋白合成。