Takeda M, Tsutsui T, Takahashi H, Hatano A, Komeyama T, Tamaki M, Koizumi T, Sato S
Department of Urology, Niigata University School of Medicine, Japan.
Urol Int. 1994;52(4):194-9. doi: 10.1159/000282607.
In 9 patients (4 male and 5 female; mean 24.7 years old) with neurogenic bladder dysfunction, diuresis renography and water filling cystometry were simultaneously monitored with a full and empty bladder, and findings of diuresis renography with a full bladder were compared with those of diuresis renography with an empty bladder. According to O'Reilly's classification, findings of diuresis renography with a full bladder were significantly worse than those of diuresis renography with an empty bladder, regardless of cystometry patterns and bladder compliances. Although every kidney without hydronephrosis on intravenous pyelogram showed normal diuresis renography with an empty bladder, some kidneys with hydronephrosis showed an obstructive pattern even with an empty bladder. These results suggest that in some patients with neurogenic bladder dysfunction, deterioration of the upper urinary tract occurs more easily with a full than with an empty bladder, regardless of bladder pressure and bladder compliance.
在9例（4例男性和5例女性；平均年龄24.7岁）神经源性膀胱功能障碍患者中，在膀胱充盈和排空时同时监测利尿肾图和水充盈膀胱测压，并将膀胱充盈时的利尿肾图结果与膀胱排空时的利尿肾图结果进行比较。根据奥赖利分类法，无论膀胱测压模式和膀胱顺应性如何，膀胱充盈时的利尿肾图结果明显比膀胱排空时的差。尽管静脉肾盂造影显示无肾积水的每个肾脏在膀胱排空时利尿肾图均正常，但一些有肾积水的肾脏即使在膀胱排空时也显示梗阻模式。这些结果表明，在一些神经源性膀胱功能障碍患者中，无论膀胱压力和膀胱顺应性如何，膀胱充盈时上尿路恶化比膀胱排空时更容易发生。
