Colon cancer connections. Cancer syndrome meets molecular biology meets histopathology.
作者信息
Smyrk T C
机构信息
Department of Pathology, Bishop Clarkson Memorial Hospital, Omaha, Nebraska 68105.
出版信息
Am J Pathol. 1994 Jul;145(1):1-6.
Abstract
摘要
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本文引用的文献
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Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis.简单重复序列中普遍存在的体细胞突变揭示了结肠癌发生的一种新机制。
Nature. 1993 Jun 10;363(6429):558-61. doi: 10.1038/363558a0.
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Microsatellite instability in cancer of the proximal colon.近端结肠癌中的微卫星不稳定性
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Clues to the pathogenesis of familial colorectal cancer.家族性结直肠癌的发病机制线索。
Science. 1993 May 7;260(5109):812-6. doi: 10.1126/science.8484121.
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Genetic mapping of a locus predisposing to human colorectal cancer.一个易患人类结直肠癌位点的基因定位。
Science. 1993 May 7;260(5109):810-2. doi: 10.1126/science.8484120.
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Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review.遗传性非息肉病性结直肠癌的遗传学、自然史、肿瘤谱及病理学：最新综述
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Hypermutability and mismatch repair deficiency in RER+ tumor cells.RER+肿瘤细胞中的高突变性和错配修复缺陷。
Cell. 1993 Dec 17;75(6):1227-36. doi: 10.1016/0092-8674(93)90331-j.
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Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer.遗传性非息肉病性结直肠癌中一种MutS同源物的突变
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Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history.结直肠癌中的基因组不稳定性：与临床病理变量及家族史的关系。
Cancer Res. 1993 Dec 15;53(24):5849-52.
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The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer.人类错配修复基因同源物MSH2及其与遗传性非息肉病性结直肠癌的关联。
Cell. 1993 Dec 3;75(5):1027-38. doi: 10.1016/0092-8674(93)90546-3.
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