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鲨肝醇对心肌的挽救作用:过氧化物酶体功能障碍在再灌注损伤中的可能作用。

Myocardial salvage by chimyl alcohol: possible role of peroxisomal dysfunction in reperfusion injury.

作者信息

Maulik N, Tosaki A, Engelman R M, Cordis G A, Das D K

机构信息

Department of Surgery, University of Connecticut School of Medicine, Farmington 06030.

出版信息

Ann N Y Acad Sci. 1994 Jun 17;723:380-4.

PMID:8030890
Abstract

The results of this study suggest that reperfusion of ischemic myocardium may lead to the peroxisomal disorder both functionally and biochemically. An alkyl glycerol such as chimyl alcohol can protect the ischemic heart from the reperfusion injury probably by enhancing the plasmalogen synthesis.

摘要

本研究结果表明,缺血心肌的再灌注可能在功能和生化方面导致过氧化物酶体紊乱。一种烷基甘油,如鲨肝醇,可能通过增强缩醛磷脂的合成来保护缺血心脏免受再灌注损伤。

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Ann N Y Acad Sci. 1994 Jun 17;723:380-4.
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