Steckler T, Keith A B, Sahgal A
MRC Neurochemical Pathology Unit, Newcastle General Hospital, Newcastle upon Tyne, UK.
Behav Brain Res. 1994 Mar 31;61(1):107-12. doi: 10.1016/0166-4328(94)90015-9.
The cholinergic pedunculopontine tegmental nucleus, located in the brainstem, and part of the reticular formation, has traditionally been linked to motor function, sleep and arousal, but has recently been implicated in cognition. To investigate this possibility, rats with radiofrequency lesions were tested on a delayed non-matching to position task, a test for spatial recognition memory abilities. Data were analysed according to the methods of signal detection theory. Lesions of the pedunculopontine nucleus did not produce marked deficits in accuracy, although there was some evidence to suggest that motivational processes could have been affected.
位于脑干且是网状结构一部分的胆碱能脚桥被盖核，传统上一直与运动功能、睡眠和觉醒相关，但最近也被认为与认知有关。为了探究这种可能性，对接受射频损伤的大鼠进行了位置延迟非匹配任务测试，这是一种空间识别记忆能力测试。数据根据信号检测理论的方法进行分析。脚桥核损伤并未在准确性上产生明显缺陷，尽管有一些证据表明动机过程可能受到了影响。
