Zhai S Q
Institute of Otorhinolaryngology of PLA, Beijing.
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1993;28(6):353-5, 382.
Forty-one patients of autoimmune inner ear disease were examined with the clinical audiometry and immunocytochemical method. The results showed that there were sensorineural hearing loss in all patients. Serum immunoglobulins (IgG, IgA, IgM) elevation in 14 of 41 patients and antibodies against inner ear tissue in 4 of 41 patients were observed. It suggests that there is specific antibody against inner ear in the serum of patients with autoimmune inner ear disease, and this disease may be originated from the cochlea or the retrocochlea. The method of clinical analyses, the standards of diagnosis and the principles of treatment were discussed.
采用临床听力学及免疫细胞化学方法对41例自身免疫性内耳病患者进行检测。结果显示，所有患者均存在感音神经性听力损失。观察到41例患者中有14例血清免疫球蛋白（IgG、IgA、IgM）升高，41例患者中有4例存在抗内耳组织抗体。提示自身免疫性内耳病患者血清中存在内耳特异性抗体，该病可能起源于耳蜗或蜗后。文中讨论了临床分析方法、诊断标准及治疗原则。
